.
This might be worth pursuing..
Protection from hurt feelings

By Kevin Lewis | July 11, 2010

Everyone has experienced pain and sickness at some point in their lives. For such physical ailments, one of the first things we do--or are instructed to do by medical providers--is take a pain reliever, like acetaminophen (a.k.a., Tylenol).

But physical pain isn’t the only kind of pain. Our feelings can also be hurt. So researchers wondered whether acetaminophen, which acts on the central nervous system, could blunt social pain, too.

In one experiment, healthy college students were randomly assigned to take acetaminophen or a placebo twice a day for three weeks. Those who took acetaminophen reported experiencing significantly fewer hurt feelings.

In a second experiment, another set of healthy college students was randomly assigned to take acetaminophen or a placebo twice a day for three weeks. At the end of the three weeks, the students were scanned in an MRI machine while playing a virtual ball-tossing game with two other players. After a while, the other players stopped tossing the ball to the subject. Those who had taken the acetaminophen exhibited significantly less neural activity in areas of the brain previously associated with experiencing social and physical pain.

DeWall, N. et al., ”Acetaminophen Reduces Social Pain: Behavioral and Neural Evidence,”
Psychological Science (forthcoming).
© Copyright 2010 The New York Times Company

Wonder if Ibuprofen (Advil, etc) would have the same effect?

Might be worth pursuing and would sure make for cheaper therapy
in some cases, especially in the earliest stages of depression.