For the experts

[LaZeR]

I dont even care if anyone called me a retard and laughed at my question and said it was dumb. I just dont like the false rumors that my intent is just to put down snus or whatever bullshit that guy was saying.

Lord, please forgive me. I just couldn't resist. ops:

[sth]

The blood nicotine level spikes like that because cigarettes are inhaled through the lungs, and therefore the drug (nicotine in this case) is absorbed and deposited into the bloodstream through the alveoli in your lungs. There is a huge surface area of alveoli in your lungs, that allows nearly all of the nicotine to be absorbed into your bloodstream incredibly quickly. Because it is absorbed so quick, it is also taken out of your system very quickly.

Snus is basically absorbed in the same manner a sublingual drug is. although it is absorbed at the buccal mucosa (your gums, if i am not mistaken, although I'm not 100% on the scientific name). This means that because snus is not smoked and the buccal mucosa has less surface area than the alveoli (not to mention the fact that the snus has much less surface area than say, the amount of cigarette smoke) your body absorbs it slower. It absorbs it slower, and therefore more evenly than if you were to smoke a cigarette. Ontop of that, you only get 20-30% of the nicotine in a pouch of snus, if im not mistaken as well.

If we were getting 100% of the nicotine, that'd be bad news for most sterk users..as well as chainsnusers

LD50's only take into account organisms that haven't been exposed to it prior (and therefore have a tolerance to it) and, they dont have sublingual listings usually. The closet one you'll get is the "oral" listing. For reference, here is the LD50 of nicotine according to the material safety data sheet on nicotine:

Oral, mouse: LD50 = 3340 ug/kg
Oral, rat: LD50 = 50mg/kg
Skin, rabbit: LD50 = 50 mg/kg
Skin, rat: LD50 = 140 mg/kg

tl;dr = nicotine spikes because it is smoked and therefore reaches the bloodstream faster.

edit: some info for people...

http://www.erowid.org/chemicals/nico...ine_dose.shtml
http://www.erowid.org/plants/tobacco...hemistry.shtml
http://www.erowid.org/chemicals/nico...a_sheet1.shtml
http://www.erowid.org/chemicals/nico...a_sheet2.shtml

edit #2: there is this though...Sold in 2.0 and 4.0 mg per piece of gum. In a 4.0 mg piece, 3.4 - 4.0 mg is considered bio-available (According to Physicians Desk Reference) -- so I may be off on my 20-30% nicotine absorption thing; my sublingual pharmacology is a little rusty lol

[Snusdog]

I dont even care if anyone called me a retard and laughed at my question and said it was dumb. I just dont like the false rumors that my intent is just to put down snus or whatever bullshit that guy was saying.

Lord, please forgive me. I just couldn't resist. ops:

Bad news Laz…. just talked to God and He assured me that you WOULD be going to hell for that one.


On a lighter note………… He also told me I was one of His favorites

.

[timoteo]

apparently alot of people (self included) think they are experts, while they are not. I thought your question about the graph was a good one, i'd be interested in seeing too.

[Markus and Joakim]

Re: For the experts

I saw a graph one time about nicotine levels comparing a snus to cigarettes. The cigarette nicotine spiked really high quickly and went down quick. The snus nicotine was more of a gradual intake and lasted longer. However, there was no data about how long the portion was used for. and i think the total time was 60 minutes. anyone have this graph or know what i am referring to?


I know there are other factors including PH, personal use, saliva etc. however. Roughly, on average. If i put in a portion of 8mg nicotine for 20 mins and than spit it out, about how much nicotine is that? Or how many cigarettes worth? im curious about how much nicotine you get with time.

Hi Paladinx,

Your comment on slower nicotine uptake relative to cigarettes is correct. We've sent away a request to some collegues to see if we have a good comparative estimate in the span of 20 minutes.

BR
J&M

[Paladinx]

Thanks guys for the feedback. I am a snus user, I enjoy the product. Just that with snus there is so much information and research etc. Much different than american tobacco products.

I have seen that graph for awhile, and i saw an expert forum, so i figured why not bring up some questions about it.

[Mattieboy27]

"weird taste of real snus"

I never said snus tasted bad, I said some of the original stuff smells like cat piss when it gets warm. I still use it, i just hate the smell of it when its not refrigerated. your just blowing smoke out of ur ass im going to ignore


anyway let me continue the conversation with anyone else on here who isn't a forum zealot. If I were to make the graph, i probably would have compared the nicotine level of a smoker having a cigarette every 30 mins, to someone who uses a portion every hour and keeps the portion in for 20 mins at a time. This would be a better comparison in my opinion. Who cares? I dunno. Maybe its dumb, its not even like I CARE, i just was always curious about it, and figured why not ask here if anyone is open to an intelligent discussion.

You're weird :roll:

[snusjus]

If you want the largest amount of nicotine from snus, I would recommend purchasing General Ekstra Sterk Los. It contains 13mg of nicotine per gram and has an 8.3 pH level. Remember, the nicotine from loose snus is absorbed more rapidly compared to portioned varieties.